In New York, in 1926, witches world is in great danger. A mysterious force causes panic on the streets of the city: the witch community is likely to remain at the mercy of loyal sponsors in Salem, a group of fanatics, determined to eliminate them forever. How about the terrible Wizard Gellert Grindelwald, it disappeared without a trace after making havoc in Europe and is still not found. Norbert Dragonneau makes its appearance in New York decided to compile a bestiary comprised of fantastic creatures. However, at the time that some of these creatures end up on the streets of the city, the disaster is imminent. The situation worsens when Percival Graves appear in the landscape.